1 It occurs in 20-57 of patients with PD within the first 3-5 years after diagnosis, and approximately. This better discrimination was more evident in the more educated group.Īddenbrooke’s Cognitive Examination Alzheimer disease Memory Impairment Screen Mini-Mental State Examination Montreal Cognitive Assessment Neuropsychological assessment Rowland Universal Dementia Assessment Scale Screening. dysfunction is one of the most common non-mo- tor symptom in Parkinsons disease (PD). The ACE-III achieved the highest diagnostic accuracy. The MoCA was introduced by Nasreddine and colleagues for assessment of cognitive functions (Nasreddine et al., 2005).It takes about 10 min to complete the test, evaluating eight domains of cognitive functions, including visuospatial and executive function, naming, memory, attention, language, abstraction, and orientation. Implementing normative data improved the diagnostic accuracy of the ACE-III but not that of the other tests. Screening tools such as the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA) can be administered in less than 15 minutes and have cutoff scores that are designed to quickly separate patients with normal versus impaired cognition. All tests, especially the ACE-III, conveyed a higher diagnostic accuracy in patients with full primary education than in the less educated group. Participants: Individuals aged 75 and older (N 199 mean age 84, 63 female). The differentiations of subtests in two scales indicate that they are complementary and could be utilized combined in clinic to improve the identification of cognitive disorders significantly. Setting: General medical service of a large teaching hospital. The weights of speech concerned subtests of MMSE are higher than those of MoCA (9/30 VS 3/30),6, 7 so patients have higher total score of MMSE than that of MoCA. Design: Cross-sectional observational study. Memory scores of the ACE-III and of the RUDAS showed a better diagnostic accuracy than those of the MMSE and of the MoCA. Objectives: To establish Montreal Cognitive Assessment (MoCA) scores that correspond to well-established cut-points on the Mini-Mental State Examination (MMSE). The Mini-ACE score from the ACE-III showed the highest diagnostic capacity (area under the curve 0.939). The area under the curve was 0.897 for the ACE-III, 0.889 for the RUDAS, 0.874 for the MMSE, 0.866 for the MIS, and 0.856 for the MoCA. MoCA scores (unadjusted for education) were transformed into equivalent MMSE scores based on the conversion table by Roalf et al. The diagnostic properties of the following tests were compared: Mini-Mental State Examination (MMSE), Addenbrooke's Cognitive Examination III (ACE-III), Memory Impairment Screen (MIS), Montreal Cognitive Assessment (MoCA), and Rowland Universal Dementia Assessment Scale (RUDAS).Īll tests yielded high diagnostic accuracy, with the ACE-III achieving the best diagnostic properties. The sensitivity and specificity of the MMSE ranged from 23 to 76 and 40 to 94, respectively, for the development of all-cause dementia. We conducted a prospective and cross-sectional study of 92 patients with mild AD and of 68 healthy controls from our Department of Neurology. Our aim was to evaluate and compare the diagnostic properties of 5 screening tests for the diagnosis of mild Alzheimer disease (AD).
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